Metabolic Screen (Urine

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Urine Metabolic Screen Lab studies request form | CPT Codes/Price List (PDF)

A metabolic screen is a battery of simple tests that is performed on urine specimens to detect the possibility of a metabolic disorder.  These tests are not specific and are used only as screening tests.  The metabolic screen includes the following:

  • Benedict's test (reducing sugars)
  • Dinitrophenylhydrazine test (keto acids)
  • Toluidine blue spot test (mucopolysaccharides)
  • Nitroprusside test (cystine, homocystine)
  • Nitrosonaphthol test (tyrosine metabolites)
  • Ferric chloride test (phenylalanine and histidine metabolites)

Specimen required:  Urine (at least 10 ml)

Transport:  Frozen on dry ice by 24-hour delivery.  The sample may be transported at ambient temperature if it is delivered to the lab on the same day it is collected.

Standard of Analysis:  Six screening tests are employed: ferric chloride, nitrosonaphthol, nitroprusside, Benedict's test, dinitrophenylhydrazine test, and toluidine blue spot test.  These are screening tests and do not necessarily confirm or exclude a particular diagnosis.  Results are compared to negative and positive controls run concurrently.

Time required: analysis is usually completed the day after receiving the specimen.

Reports:  Written reports with interpretation are mailed to the referring physician and when an abnormality is detected the report will also be telephoned to the referring physician.

Special requests: Other tests for metabolic disorders are available and may be appropriate following the screening test.  Special requests or questions should be directed to the laboratory.

CPT Code:  84377, 83866, 84035, 84510, 81005

 

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Greenwood Genetic Center

Diagnostic Laboratories

125 Gregor Mendel Circle, Greenwood, SC  29646

864-941-8111; 800-473-9411 (toll-free)

fax: 864-941-8133