Eric Bend, PhD

Fellow, Molecular Diagnostic Laboratory

EricBendDr. Bend's work has focused on the fundamental mysteries of neuron function and neuronal disease. As a graduate student, he elucidated novel molecular interactions that drive neurotransmitter release at synapses. In his postdoctoral research, Dr. Bend used genome engineering in the model organism C. elegans to test the pathogenicity of novel human ion channel variants. 

Dr. Bend spent a year at GGC under Dr. Charles Schwartz, implementing CRISPR/Cas9 genome engineering in human cell lines to study the etiology of familial split-hand/foot malformation and inherited macrocephaly and overgrowth.

In the summer of 2016, Dr. Bend joined GGC's diagnostic lab as a Clinical Molecular Fellow. He has a great interest in the explosion of new genomic technologies and their implications for diagnosing and treating genetic diseases.

Selected Publications

  • Bend EG, Si Y, Stevenson DA, Bayrak-Toydemir P, Newcomb TM, Jorgensen EM, and Swoboda KJ. NALCN channelopathies: Distinguishing gain-of-function and loss-of-function mutations. Neurology. epub August 24, 2016.  Open Access

  • Jang S, Nelson JC, Bend EG, Rodríguez-Laureano L, Tueros FG, Cartagenova L, Underwood K, Jorgensen EM, Colón-Ramos DA. Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function. Neuron. 2016; 90(2):278-291Z. Full text

  • Rawson RL, Yam L, Weimer RM, Bend EG, Hartwieg E, Horvitz HR, Clark SG, Jorgensen EM. Axons degenerate in the absence of mitochondria in C. elegans. Curr Biol. Mar 31 2014.

  • Rathore SS*, Bend EG*, Yu H, Hammarlund M, Jorgensen EM, Shen J. Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex. Proc Natl Acad Sci. Dec 28 2010. (*equal contribution)

  • Marinov BS, Bend EG, Abramson JJ. Reactions with dye free radicals reveal weak redox properties of drugs. Photochem Photobiol. Nov. 2006

Education

  • B.A. Biology, Lewis and Clark College, Portland, OR, 2002
  • Ph.D. Neuroscience, University of Utah, Salt Lake City, UT, 2013
  • Fellow, University of Utah, Salt Lake City, UT, 2013-2015
  • Fellow, JC Self Research Institute, Greenwood Genetic Center, 2015-Present

Contact Information

Office (864) 388-8112
Fax (864) 941-8141
ebend@ggc.org
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