Michael J. Lyons, MD

Assistant Clinical Geneticist – Charleston Office

Dr. Lyons is a clinical geneticist involved in the evaluation of genetic disorders in individuals of all ages. His areas of interest include dysmorphology, single gene disorders, genetics education, and treatment of genetic disorders.

Dr. Lyons is certified by the American Board of Medical Genetics (2005) and the American Board of Pediatrics (2000). He is a fellow of the American College of Medical Genetics and the American Academy of Pediatrics. He holds membership in the American Academy of Pediatrics Section on Genetics and Birth Defects, American Society of Human Genetics, American Medical Association, Charleston County Medical Society, and the South Carolina Medical Association.

Selected Publications

• Veerapandiyan A, Abdul-Rahman OA, Adam MP, Lyons MJ, Manning M, Coleman K, Kobrynski L, Taneja D, Schoch K, Zimmerman HH, Shashi V. Chromosome 22q11.2 deletion syndrome in African-American patients: A diagnostic challenge. Am J Med Genet A. 2011 Sep;155(9):2186-95.

• Edens AC, Lyons MJ, Duron RM, Dupont BR, Holden KR. Autism in two females with duplications involving Xp11.22-p11.23. Dev Med Child Neurol. 2011 May;53(5):463-6.

• Lyons MJ, Duron R, Molinero I, Sanguiuolo F, Holden KR. Novel CLCN1 mutation in carbamazepine-responsive myotonia congenita. Pediatr Neurol. 2010 May;42(5):365-8.
  
  
• Takano K, Lyons M, Moyes C, Jones J, Schwartz CE. Two percent of patients suspected of having Angelman syndrome have TCF4 mutations. Clin Genet. 2010 Sept;78(3):282-8
  
  
• Clark RD, Graham JM Jr, Friez MJ, Hoo JJ, Jones KL, McKeown C, Moeschler JB, Raymond FL, Rogers RC, Schwartz CE, Battaglia A, Lyons MJ, Stevenson RE. FG syndrome, an X-linked multiple congenital anomaly syndrome: The clinical phenotype and an algorithm for diagnostic testing. Genet Med. 2009 Nov;11(11):769-77.
  
  
• Lyons MJ, Graham JM Jr, Neri G, Hunter AG, Clark RD, Rogers RC, Moscarda M, Boccuto L, Simensen R, Dodd J, Robertson S, Dupont BR, Friez MJ, Schwartz CE, Stevenson RE. Clinical experience in the evaluation of 30 patients with a prior diagnosis of FG syndrome. J Med Genet. 2009 Jan;46(1):9-13.
  
  
• Hilton E, Johnston J, Whalen S, Okamoto N, Hatsukawa Y, Nishio J, Kohara H, Hirano Y, Mizuno S, Torii C, Kosaki K, Manouvrier S, Boute O, Perveen R, Law C, Moore A, Fitzpatrick D, Lemke J, Fellmann F, Debray FG, Dastot-Le-Moal F, Gerard M, Martin J, Bitoun P, Goossens M, Verloes A, Schinzel A, Bartholdi D, Bardakjian T, Hay B, Jenny K, Johnston K, Lyons M, et al. BCOR analysis in patients with OFCD and Lenz microphthalmia syndromes, mental retardation with ocular anomalies, and cardiac laterality defects. Eur J Hum Genet. Oct;17(10):1325-35.
  
  
• Lyons MJ (June 2008) MED12-Related Disorders in: GeneReviews at GeneTests: Medical Genetics Information Resource [database online]. Copyright, University of Washington, Seattle, 1997-2008. Available at http://www.genetests.org.
  
  
• Rice G, Patric T, Parmar, R, Taylor CF, Aeby A, Aicardi J, Artuch R, Montalto SA, Bacino CA, Barroso B, Baxter P, Benko WS, Bergmann C, Bertini E, Biancheri R, Blair EM, Blau N, Bonthron DT, Briggs T, Brueton LA, Brunner HG, Burke CJ, Carr IM, Carvalho DR, Chandler KE, Christen HJ, Corry PC, Cowan FM, Cox H, D’Arrigo S, Dean J, De Laet C, De Praeter C, Dery C, Ferrie CD, Flintoff K, Frints SG, Garcia-Cazorla A, Gener B, Goizet C, Goutieres F, Green AJ, Guet A, Hamel BC, Hayward BE, Heiberg A, Hennekam RC, Husson M, Jackson AP, Jayatunga R, Jian YH, Kant SG, Kao A, King MD, Kingston HM, Klepper J, van der Knaap MS, Kornberg AJ, Kotzot D, Kratzer W, Lacombe D, Lagae L, Landrieu PG, Lanzi G, Leitch A, Lim MJ, Livingston JH, Lourenco CM, Lyall EG, Lynch SA, Lyons MJ, et al. Clinical and molecular phenotype of Aicardi-Goutieres syndrome. Am J Hum Genet. Oct;81(4):713-25.
  
  
• Lyons MJ, Wood T, Espinoza L, Holden KR. Early Onset Alpha-Mannosidosis with mild progression in a Hispanic male. Proc Greenwood Genetic Center 25:44-47, 2006.
  
  
• Lin RJ, Cherry AM, Chen KC, Lyons MJ, Hoyme HE, Hudgins L. Terminal deletion of 6p results in a recognizable phenotype. Am J Med Genet 136(2):162-8, 2005.