Focused Exome

In order to best meet the needs of the clinical providers and patients we serve, our molecular laboratory offers custom testing options, or Focused Exomes, for sequencing of single genes and multi-gene panel requests. These customizable tests are next generation sequencing based assays utilizing our whole exome sequencing platform, the Agilent SureSelect Clinical Research Exome kit.


Healthcare providers can select from one up to 15 genes for these focused exome requests. While a focused exome can include more than 15 genes, these are considered on a case by case basis. We recommend you contact the laboratory and discuss the case and gene(s) of interest with one of our laboratory genetic counselors or directors prior to submitting the test order.


Focused exomes may have low coverage for certain exons, genes, or regions included in the request given the nature of an exome platform. These details can be reviewed and discussed on an individual case basis. Similar to whole exome sequencing and our established NGS panels, all variants are confirmed with Sanger sequencing before being reported out. We hope that the option of a focused exome will provide flexible and efficient diagnostic tests for those patients that don't have other appropriate testing options.

One Gene - $1,500
Custom panel - $3,000
CPT codes depend upon the gene(s) requested

Diagnostic Laboratory Accreditations and Licenses

The Greenwood Genetic Center's Diagnostic Laboratories are commited to providing the highest-quality genetic testing with a strenuous quality control program in place. The labs hold the following current certifications of accreditation and licensure:

CLIA Certificate of Accreditation

CAP Certificate of Accreditation

Florida License

Maryland License

Pennsylvania Permit

Pennsylvania Permit

Billing Policy

IN-STATE (SOUTH CAROLINA) SAMPLES

INSURANCE – South Carolina Residents ONLY

The Greenwood Genetic Center will file the patient's insurance. Please provide a copy of the front and back of the patient's insurance card with the specimen. In addition, please include the insured's date of birth and relationship to the patient as well as any preauthorizations that may be needed prior to testing.  Use the link below to determine which insurance groups are considered in network with GGC and which require pre-authorization.

Insurance Contract List

INSTITUTIONAL BILLING

Referring clinics, hospitals, labs, and/or physicians may establish Institution accounts with convenient monthly invoicing and payment options.

If you are interested in setting up an account for your institution, please complete the Institutional Account Request Form and contact our billing department at 1-864-941-8117.

SELF-PAY

Self-pay is available to individuals without insurance. Tests that are paid for in advance (payment received when the sample arrives at the lab) will be given a 20% discount. We accept the following methods of payment to accompany the sample:

  • Check
  • Visa
  • MasterCard
  • Money Order

Financial assistance or payment plans may be available in some self-pay situations. Please contact us for additional information.

OUT-OF-STATE SAMPLES

INSURANCE

We do not accept out of state insurance for any tests except the next generation sequencing tests listed below. The Billing Form must be completed and submitted with the sample for NGS panel tests. Blue Cross Blue Shield enrollees are not eligible for this option, and out-of-state Medicaid is not accepted.

  • NGS Aortic Dysfunction/Dilation and Related Disorders Panel
  • NGS Autism Panel
  • NGS Congenital Disorders of Glycosylation (CDG) Panel
  • NGS Connective Tissue Disorders Panel
  • NGS Craniosynostosis Panel
  • NGS Epilepsy/Seizures Panel
  • NGS Lysosomal Storage Diseases Panel
  • NGS Neuronal Ceroid Lipofuscinoses Panel
  • NGS Non-immune Hydrops Panel
  • NGS Overgrowth/Macrocephaly Panel
  • NGS Peroxisomal Biogenesis Disorders Panel
  • NGS RASopathy Panel
  • NGS 2nd Tier Rett/Angelman Panel
  • NGS Skeletal Dyplasias Panel
  • NGS Syndromic Autism Panel
  • NGS XLID Panel

All other tests are subject to institutional billing or self-pay.

INSTITUTIONAL BILLING

Referring clinics, hospitals, labs, and/or physicians may establish Institution accounts with convenient monthly invoicing and payment options.

If you are interested in setting up an account for your institution, please complete the Institutional Account Request Form and contact our billing department at 1-864-941-8117.

SELF-PAY

Self-pay is available to out-of-state (non-South Carolina residents) patients without insurance. Tests that are paid for in advance (payment received when the sample arrives at the lab) will be given a 20% discount.  We accept the following methods of payment in advance:

  • Check
  • Visa
  • MasterCard
  • Money Order

Financial assistance may be available for self-pay patients. Please contact us for additional information.

INTERNATIONAL SAMPLES

Payment must be received with the sample. We accept the following methods of payment:

  • Certified check in US dollars drawn on a US bank
  • Visa
  • MasterCard
  • Wire Transfer

For other billing or insurance questions, please contact our insurance/patient accounts department at 1-800-273-8840.

Tests that are paid for in advance (payment received when the sample arrives at the lab) will be given a 20% discount

Diagnostic Laboratory Requisition Forms

All samples submitted to the GGC Diagnostic Laboratory must be accompanied by the appropriate request form. 
Please use one of the forms listed below.

 

Biochemical Lab Request Form

Cancer Testing Request Form

Cytogenetics Request Form

MetaSign (metabolomics) Request Form

Molecular Lab Request Form

NGS Panel Request Form

NBS Follow-up Request Form

Whole Exome Sequencing Request Form (proband)

Pennsylvania Permit

Molecular Diagnostic Lab

The Molecular Diagnostic Laboratory of the Greenwood Genetic Center offers DNA analysis for many genetic disorders via gene sequencing, targeted mutation analysis, MLPA deletion/duplication testing, trinucleotide repeat analysis and next generation sequencing panels. Testing is available for both common and rare genetic disorders with a special interest in conditions involving X-linked intellectual disability. Prenatal diagnosis is also available for many of these disorders. The close relationship between the GGC’s Molecular Diagnostic Laboratory and Research Division allows for a smooth transition from scientific discovery to diagnostic testing. Contact our laboratory directors for further information on any of our testing options.

Molecular Diagnostic Request Form

NGS Panel Request Form

Study Participation

Eligible participants include individuals at all ages who have had complete MECP2 gene analysis and have the clinical diagnosis of classic or variant Rett syndrome, with or without mutations in the gene OR individuals without clinical Rett syndrome but with MECP2 mutations.

For more information, see the Rett syndrome study fact sheet or contact This email address is being protected from spambots. You need JavaScript enabled to view it. , study coordinator.