Carnitine Analysis, Total and Free

Test description Carnitine plays an important role in the transport of long chain fatty acids into the mitochondria as well as the formation of acylcarnitines.
Indications Measurement of free and total carnitine levels are important for determining the validity of acylcarnitine profiles as well as following patients under carnitine supplementation.

For patients with low plasma carnitine and a suspected carnitine uptake disorder, urine carnitine (total and free) is available as further testing.
Methodology Analysis will be done by tandem mass spectrometry (MS-MS).
Associated Tests Total and free carnitine analysis is also part of our Biochemical Genetics Profile.
Specimen Requirements Plasma Carnitine - 5-7 mL of peripheral blood should be collected in a sodium heparin blood tube. Plasma should be removed and frozen prior to shipment. Approximately 1 mL of plasma is needed for analysis. Blood spots are not acceptable.

Urine Carnitine - 5 mL of random catch urine is requested.  The minimum volume required is 1 mL.  Samples must be frozen, preferably on dry ice.  Samples should be sent frozen by overnight delivery services or courier.  If the sample can be delivered the same day, it may be sent cold or at room temperature.
Transport Frozen samples should be sent overnight express.
Turnaround time 10 days (each sample)
CPT Codes

Plasma only - 82379
Urine only - 82379
Plasma and urine - 82379 (x2)

Cost Plasma only - $120
Urine only - $120
Plasma and urine - $240
Contact For further information contact This email address is being protected from spambots. You need JavaScript enabled to view it. , MS or Tim Wood, PhD at 1-800-473-9411

Biochemical Lab

The Biochemical Lab provides diagnostic and screening tests for a variety of inherited metabolic disorders.

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