Metabolic Screen - Urine

Test description Our metabolic screen is a battery of simple tests that is performed on urine specimens to detect the possibility of a metabolic disorder.  These tests are not specific and are used only as screening tests.  The metabolic screen includes the following:
  • Benedict's test (reducing sugars)
  • Dinitrophenylhydrazine test (keto acids)
  • Toluidine blue spot test (mucopolysaccharides)
  • Nitroprusside test (cystine, homocystine)
  • Nitrosonaphthol test (tyrosine metabolites)
  • Ferric chloride test (phenylalanine and histidine metabolites)
Methodology Six screening tests are employed: ferric chloride, nitrosonaphthol, nitroprusside, Benedict's test, dinitrophenylhydrazine test, and toluidine blue spot test.  These are screening tests and do not necessarily confirm or exclude a particular diagnosis. Results are compared to negative and positive controls run concurrently.
Associated Tests For a more comprehensive metabolic assessment see our Biochemical Genetics Profile
Specimen Requirements Urine (at least 10 ml)
Transport Frozen on dry ice by 24-hour delivery. The sample may be transported at ambient temperature if it is delivered to the lab on the same day it is collected.
Turnaround time 5 days
CPT Codes 84377, 84035, 84510, 82615, 81005
Cost $100
Contact For further information contact Kellie King, MS or Tim Wood, PhD at 1-800-473-9411

Biochemical Lab

The Biochemical Lab provides diagnostic and screening tests for a variety of inherited metabolic disorders.

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