Urine Oligosaccharide Analysis

Test description The urine oligosaccharide analysis is a semi-quantitative test useful in screening for alpha mannosidosis, beta mannosidosis, fucosidosis, sialidosis, beta galactosidase deficiency, galactosialidosis, Sandhoff disease, and aspartylglucosaminuria.  Specific lysosomal enzyme analysis is necessary to confirm a diagnosis.
Methodology Oligosaccharides are analyzed liquid chromatography tandem mass spectrometry (LC-MS/MS). 

This new methodology improves the sensitivity and specificity of the test leading to fewer false positives. 
Associated Tests

Urine oligosaccharide analysis is also available on the Storage Disease Screening Panel.

Lysosomal enzyme testing may be indicated if urine oligosaccharides are elevated. Enzymes can be ordered individually or as part of a panel.

Dried Blood Spot Lysosomal Enzyme Panel

Lysosomal Enzyme Panel

Oligosaccharidoses Enzyme Panel

Specimen Requirements Urine (3 ml minimum)
Transport Urine should be sent frozen on dry ice by courier or 24 hour delivery. Specimens may be brought by courier at ambient temperature if it can be delivered on the day of collection.
Turnaround time 21 days
CPT Codes 84377
Cost $250
Contact For further information contact one of our This email address is being protected from spambots. You need JavaScript enabled to view it. at 1-800-473-9411.

 

liquid chromatography tandem mass spectrometry (LC-MS/MS).  This new methodology improves the sensitivity and specificity of the test leading to fewer false positives. 

Biochemical Lab

The Biochemical Lab provides diagnostic and screening tests for a variety of inherited metabolic disorders.

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