864-941-8177 (voice)
864-941-8133 (fax)
tim@ggc.org |
Director - Biochemical Genetics Laboratory
- B.S. (Biology) - Samford University, Birmingham, AL,
1993
- M.S. (Zoology) - Southern Illinois University at
Carbondale, Carbondale, IL, 1995
- Ph.D. (Human Genetics) - University of Alabama at
Birmingham, Birmingham, AL, 2000
- Clinical Molecular Fellow and Biochemical Fellow,
Greenwood Genetic Center, 2000-04
- Asst. Director, Biochemical Genetics Laboratory,
Greenwood Genetic Center, 2004-06
- Director, Biochemical Genetics Laboratory, Greenwood
Genetic Center, 2006-present
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Dr. Wood came to the Greenwood Genetic Center (GGC) as a
clinical laboratory fellow in 2000. After completing fellowships in clinical
molecular and clinical biochemical genetics, he was named assistant director of
the biochemical genetics laboratory. In 2006 he was promoted to director. Dr.
Wood is currently ABMG certified in both clinical molecular and clinical
biochemical genetics.
Dr. Wood is a member of the Society of Inherited Metabolic
Disease, the Society for the Study of Inborn Errors of Metabolism, the American
Society of Human Genetics and is a fellow of the American College of Medical
Genetics. Dr. Wood serves on the board of directors for the Southeastern
Regional Genetics Group and is a member of the South Carolina Newborn Screening
Advisory Committee.
The GGC biochemical laboratory has a broad focus and serves as
a clinical testing center for South Carolina, including follow up testing for
expanded newborn screening. The laboratory specializes in the diagnosis of
lysosomal storage disorders, congenital disorders of glycosylation, and creatine
biosynthesis disorders.
Selected Publications:
- Hahn KA, Salomons GS, Tackels-Horne D, Wood TC,
Taylor HA, Schroer RJ, Lubs HA, Jakobs C, Olson RL, Holden KR, Stevenson RE,
Schwartz CE: X-linked mental retardation with seizures and carrier
manifestations is caused by a mutation in the creatine-transporter gene
(SLC6A8) located in Xq28. Am J Hum Genet 70:1349-1356, 2002.
- Li P, Wood, TC, Thompson JN: Diversity of
mutations and distribution of single nucleotide polymorphic alleles in the
human ∞-L-iduronidase (IDUA) gene. Genetics In Medicine 4:420-426, 2002.
- Cason AL, Ikeguchi Y, Skinner C, Wood TC, Holden
KR, Lubs HA, Martinez F, Simensen RJ, Stevenson RE, Pegg AE, Schwartz CE:
X-linked spermine synthase gene (SMS) defect: the first polyamine deficiency
syndrome. Eur J Hum Genet 11:937-944, 2003.
- Clark AJ, Rosenburg EH, Almeida LS, Wood TC,
Jakobs C, Stevenson RE, Schwartz CE, Salomons GS: X-linked creatine
transporter (SLC6A8) mutations in about 1% of males with mental retardation
of unknown etiology. Hum Genet 119:604-610, 2006.
- Schimmenti LA, Crombez EA, Schwahn BC, Heese BA, Wood
TC, Schroer RJ, Bentler K, Cederbaum S, Sarafoglou K, McCann M, Rinaldo
P, Matern D, Amat di San Filippo C, Pasquali M, Berry SA, Longo N: Expanded
newborn screening identifies maternal primary carnitine deficiency. Mol
Genet Metab 90:441-445, 2007.
- Lyons MJ, Wood T, Espinoza L, Stensland HM, Holden
KR: Early onset alpha-mannosidosis with slow progression in three Hispanic
males. Dev Med Child Neurol 49:854-857, 2007.
Books / Chapters
- Young S, Struys E, Wood TC: Quantification of
creatine and guanidinoacetate using GC/MS and LC-MS/MS for the detection of
cerebral creatine deficiency syndromes. Current protocols series. Unit 17.3.
July 2007.
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