Mattie joined the Greenwood Genetic Center in 2021 as a genetic assistant in the Greenwood office. Her roles include obtaining insurance authorizations and supporting the Greenwood clinic by obtaining and reviewing family and medical history and providing assistance throughout patient appointments. Mattie is also involved in GGC’s initiation of eVisits and eConsults that will enhance patient experiences and access to genetics services.
Office: (864) 943-4332
Fax: (864) 388-1062
North Greenville University, B.S., Biology, 2020
Talitha joined the Greenwood Genetic Center in 2014 as an HR Generalist. She received a B.S. degree in Business Administration with an emphasis in Healthcare
Management from Lander University in 2014.
During her time at the Center, she has played an instrumental role in modernizing payroll and benefits processes, creating a digital footprint, onboarding,
and educating new employees. Talitha possesses experience in several aspects of human resources including time-attendance and pay processes, benefits
management, recruitment, employee relations, and change management.
She has served on the board of the Piedmont Area Human Resource Association (PAHRA), a local SHRM chapter, since 2019, currently serving as the President.
Office (864) 941-8125
Fax (864) 388-1062
- B.S., Business Administration – Healthcare Management, Lander University, 2014
After receiving his Ph.D. degree from China Agricultural University in Beijing, China, Dr. Wang joined Columbia University in New York City as a postdoctoral
fellow, where he studied the field of epigenetics. By transitioning to work in the clinical laboratories, he was attracted to the diagnosis of genetic
disorders by utilizing the cytogenetic and molecular methods. He specialized in developing new approaches and testing and interpreting the data for
clinical diagnostics of human diseases by leveraging next-generation sequencing and conventional Sanger sequencing analyses, as well as other molecular
methodologies. In 2020, he continued to pursue his career goal in clinical genetic medicine through the Laboratory Genetics and Genomics fellowship
at GGC. Currently, he is training in interpreting the diagnostic results of both cytogenetic and molecular tests, as well as developing novel tests
for clinical use.
- B.S., Bioengineering, Dalian University of Technology, Dalian, Liaoning, China, 2006
- Ph.D., Microbiology, China Agricultural University, Beijing, China, 2011
- Fellow, Laboratory Genetics and Genomics, Greenwood Genetic Center, 2020-present
- Zhurinsky, J., Salas-Pino, S., Iglesias-Romero, A., Torres-Mendez, A., Knapp, B., Flor-Parra, I., Wang, J., Bao, K., Jia, S., Chang,
F., Daga, R. (2019) Effects of the Microtubule Nucleator Mto1 on Chromosomal Movement, DNA Repair, and Sister Chromatid Cohesion in Fission Yeast.
Mol Biol Cell. 30(21):2695-2708
- Zhang, Y. #, Shan, C.#, Wang, J.#, Bao K.#, Tong, L.*, and Jia, S.* (2017). Molecular basis for the role of oncogenic histone mutations
in modulating H3K36 methylation. Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation. Sci Rep. 2017 Mar
3;7:43906. (# co-first author).
- Wang, J., Cohen, A.L., Letian, A., Tadeo, X., Moresco, J.J., Liu, J., Yates, J.R., Qiao, F., and Jia, S. (2016). The proper connection
between shelterin components regulates telomeric heterochromatin assembly. Genes Dev. 30,827-839.
- Wang, J., and Jia, S. New insights into the regulation of heterochromatin. (2016).Trends in Genetics. 32, 284-294.
- Shan, C.#, Wang, J.#, Xu K.#, Chen, H., Andrews, S., Moresco, J. J., Yates, J. R., Nagy, P. L., Tong, L.*, and Jia, S.* (2016). Histone
H3K9M mutation traps a H3K9 methyltransferase to block heterochromatin spreading. eLife 5:e17903. (# co-first author).
- Wang, J., Reddy, B.D., and Jia, S. (2015). Rapid epigenetic adaptation to uncontrolled heterochromatin spreading. eLife 4, 1–17.
- Wang, J., Tadeo, X., Hou, H., Andrews, S., Moresco, J.J., Yates, J.R., Nagy, P.L., and Jia, S. (2014a). Tls1 regulates splicing of
shelterin components to control telomeric heterochromatin assembly and telomere length. Nucleic Acids Res. 1–14.
- Wang, J., Lawry, S.T., Cohen, A.L., and Jia, S. (2014b). Chromosome boundary elements and regulation of heterochromatin spreading.
Cell. Mol. Life Sci. 71, 4841-4852.
- Wang, J., Tadeo, X., Hou, H., Tu, P.G., Thompson, J., Yates, J.R., and Jia, S. (2013). Epe1 recruits BET family bromodomain protein
Bdf2 to establish heterochromatin boundaries. Genes Dev. 27, 1886–1902.
- Tadeo, X., Wang, J., Kallgren, S.P., Liu, J., Reddy, B.D., Qiao, F., and Jia, S. (2013). Elimination of shelterin components bypasses
RNAi for pericentric heterochromatin assembly. Genes Dev. 27, 2489–2499.
- Hou, H., Zhou, Z., Wang, Y., Wang, J., Kallgren, S.P., Kurchuk, T., Miller, E. a, Chang, F., and Jia, S. (2012). Csi1 links centromeres
to the nuclear envelope for centromere clustering. J. Cell Biol. 199, 735–744.
- Wang, J., Hu, Q., Chen, H., Zhou, Z., Li, W., Wang, Y., Li S., and He Q. (2010). Role of Individual Subunits of the Neurospora crassa
CSN Complex in Regulation of Deneddylation and Stability of Cullin Proteins. PLoS Genet 6 (12) e1001232.
- Xu, H., Wang, J., Hu, Q., Quan, Y., Chen, H., Cao, Y., Li, C., Wang, Y., and He, Q. (2010). DCAF26, an adaptor protein of Cul4-based
E3, is essential for DNA methylation in Neurospora crassa. PLoS Genet 6 (11) ,e1001132.
- Zhao, Y., Shen, Y., Yang, S., Wang, J., Hu, Q., Wang, Y., and He, Q. (2010). Ubiquitin ligase components Cullin4 and DDB1 are essential
for DNA methylation in Neurospora crassa. J Biol Chem 285, 4355-4365.
Meg graduated from the University of South Carolina Genetic Counseling Program and joined the Greenwood Genetic Center in 2020. Meg provides genetic counseling
in the general genetics clinic for pediatric and adult patients. She is certified by the American Board of Genetic Counseling and is a member of the
National Society of Genetic Counselors.
Office (843) 735-5096
- B.A. Biological Sciences, Clemson University, 2017
- M.S. Genetic Counseling, University of South Carolina, 2020
Brian joined the Greenwood Genetic Center (GGC) in 2020. He oversees the daily administrative operations of the GGC clinics and works collaboratively with
the Director of Clinical Services to ensure efficient and stable operations and the highest level of quality patient care across all GGC clinic sites.
He comes to the GGC after 23 years of service in the Marine Corps.
Office (864) 941-8161
- B.S., Systems Engineering, United States Naval Academy, Annapolis, MD, 1997
- M.A. and Distinguished Graduate, Strategic Studies, United States Army War College, Carlisle, PA, 2016
Falecia graduated from the University of South Carolina Genetic Counseling Program and joined the Greenwood Genetic Center in 2020. She serves as a liaison
between the GGC Diagnostic Laboratories and our network of referring physicians, genetic counselors, and other healthcare providers. Falecia is certified by the American Board of Genetic Counseling.
Office (864) 941-8190
Fax (864) 941-8141
- B.S., Biology, University of North Carolina Chapel Hill, 2018
- M.S., Genetic Counseling, University of South Carolina School of Medicine, 2020
Ellen graduated from the University of South Carolina Genetic Counseling Program and joined the Greenwood Genetic Center in 2020. Ellen provides genetic
counseling in general, metabolic, and oncology clinics. She is a member of the National Society of Genetic Counselors and is certified by the American Board of Genetic Counseling.
Office (864) 388-1724
Fax (864) 941-8114
- B.S. Biological Sciences, University of South Carolina, 2011
- M.S. Biological Sciences, University of South Carolina, 2014
- M.S. Genetic Counseling, University of South Carolina, 2020
- Yuqi Qiu, Thomas Arbogast, Sandra Martin Lorenzo, Hongying Li,1 Shih C. Tang, Ellen Richardson, Oanh Hong, Shawn Cho, Omar Shanta, Timothy Pang, Christina Corsello, Curtis K. Deutsch, Claire Chevalier, Erica E. Davis, Lilia M. Iakoucheva, Yann Herault, Nicholas Katsanis, Karen Messer, Jonathan Sebat, Oligogenic Effects of 16p11.2 Copy-Number Variation on Craniofacial Development, Cell Reports, Volume 28, Issue 13, 24 September 2019, Pages 3320-3328.
- Anna Lindstrand, Stephan Frangakis, Claudia M.B. Carvalho, Ellen B. Richardson, Kelsey A. McFadden, Jason R. Willer, Davut Pehlivan, Pengfei Liu, Igor L. Pediaditakis, Aniko Sabo, Richard Alan Lewis, Eyal Banin, James R. Lupski, Erica E. Davis, Nicholas Katsanis, Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl Syndrome, The American Journal of Human Genetics, Volume 99, Issue 2, 4 August 2016, Pages 318-336, ISSN 0002-9297, http://dx.doi.org/10.1016/j.ajhg.2015.04.023
Bill Tiller joined GGC as the Executive Director of the GGC Foundation in 2020. Bill comes to GGC with a long and successful career in fundraising and
development, working primarily in the areas of children’s health and advocacy. He has secured and directed approximately $43 million to support numerous
nonprofit organizations including The Meyer Center for Special Children, Make-A-Wish Foundation of SC, and most recently served as President and CEO
of the Pediatric Brain Tumor Foundation.
- Pediatric Brain Tumor Foundation, President and CEO, 2019
- Make-A-Wish SC, President and CEO, 2014-2019
- Meyer Center for Special Children, Director of Development, 2012-2014
- Presbyterian College, Director Development for Major Gifts, 2011-2012
- Thornwell Home for Children, VP for Advancement, 2006-2011
- United Way of Laurens County, Executive Director, 1999-2005
Bachelor’s Degree (Political Science and Government) Clemson University, 1988.
Office: (864) 388-1813
Holly Crozier is a registered dietitian with the Greenwood Genetic Center’s metabolic treatment team. She joined the Greenwood Genetic Center in 2019 from
Indianapolis, Indiana where she worked at Riley Children’s Hospital at IU Health as a neurology/ketogenic dietitian and as part of a craniofacial feeding
team. Holly is based out of GGC’s Greenville office providing medical nutrition therapy, nutrition assessment and follow-up for individuals with inborn
errors of metabolism. She also provides follow-up and coordination of nutrition services for individuals with inborn errors of metabolism between clinic
Holly is a member of Genetic Metabolic Dietitians International, the Academy of Nutrition and Dietetics, the South Carolina Academy of Nutrition and Dietetics,
and the Pediatric Nutrition Practice Group. Holly served as the Scholarship Chair for the Central Indiana Academy of Nutrition and Dietetics from 2018-2019.
Office: (864) 672-6909
Fax: (864) 371-6910
- M.S., Nutrition Science, Applied Health Science, Indiana University, 2017
- B.S., Secondary Education, Indiana University, 2003
Shelly joined GGC’s DNA Diagnostic Laboratory in 2019 as Molecular Specialist. She is responsible for clinical and diagnostic data review to identify genetic
variants and systematically assess their pathogenicity based on American College of Medical Genetics and Genomics (ACMG) guidelines.
Her graduate research was at the Clemson University Genomics Institute and the Arizona Genomics Institute where the primary focus was studying the evolutionary,
structural, and functional genomics of crop plants. Since earning her Master’s degree, she has worked as a Field Applications Scientist for Roche Diagnostics
and at ThermoFisher with their next generation sequencing portfolio. Shelly also previously worked at GGC as a lab technologist from 2005-07. She is
a member of the Association of Genetic Technologists and is currently pursuing a Master’s in Business Administration.
Office (864) 941-8172
Fax (864) 941-8141
- B.S., Biological Sciences, Clemson University, 1998
- M.S., Genetics, Clemson University, 2003
- Lovell C, Decker P, Thompson S. Analysis of a Diverse Assemblage of Diazotrophic Bacteria from Spartina alterniflora using DGGE and
Clone Library Screening. Journal of Microbiological Methods. 2008: 160-171.
- The Rice Chromosome 10 Sequencing Consortium. In-Depth View of Structure, Activity, and Evolution of Riche Chromosome 10 Science. 2003; 1566-1569.
- The Rice Chromosome 3 Sequencing Consortium. Sequence, Annotation, and Analysis of Synteny Between Rice Chromosome 3 and Diverged Grass Species. Genome
Research. 2005: 1284-1291.
- Thompson, S. “Sequence Analysis of a 500kb Region of Rice Chromosome 3.” Thesis. Clemson University, 2003.