Flanagan-Steet, Heather

Director of Functional Studies

Flanagan-Steet, Heather

Dr. Flanagan-Steet's research has largely focused on defining the mechanisms governing early tissue development. This has ranged from investigating how neuromuscular synapses form to development of the embryonic heart and craniofacial skeleton. Over the last thirteen years Dr. Flanagan-Steet’s efforts have centered on defining the molecular and cellular mechanisms underlying pathogenesis of rare genetic diseases. This has included several lysosomal storage disorders (LSDs) as well as the congenital disorders of glycosylation (CDGs). Her work on genetic diseases has largely involved generating zebrafish models to investigate gene function and disease pathogenesis. Her work pioneered the use of zebrafish to model rare inherited diseases, bringing new insight into the molecular initiators and mechanisms underlying pathogenesis of mucolipidosis II and PMM2-CDG. The success of these studies has been augmented by her long time collaboration with her colleague and spouse, Dr. Richard Steet. In her role as Director of Functional Studies she works closely with the Center’s tremendous team to advance our understanding of rare diseases.

Dr. Flanagan-Steet's Active Research Project Page

Contact Information

Office: (864) 388-1806
Fax (864) 388-1707
heatherfs@ggc.org

Education

  • B.A. (Biology), Carleton College, Northfield, MN, 1994
  • Ph.D. (Molecular, Cellular, and Developmental Biology), University of Colorado-Boulder, Boulder, CO, 2001
  • Postdoctoral Fellow, Washington University School of Medicine, St. Louis, MO  2001-2005

Professional Appointments

  • Director of Aquatic Operations, Complex Carbohydrate Research Center, University of Georgia, 2006-2018
  • Assistant Research Professor, Complex Carbohydrate Research Center, University of Georgia, 2009-2013
  • Graduate Faculty,  Department of Biochemistry and Molecular Biology, University of Georgia, 2011-2018
  • Associate Research Professor, Complex Carbohydrate Research Center, University of Georgia, 2013-2018
  • Director of Functional Studies, Greenwood Genetic Center, 2018-present

Other Appointments and Professional Service

  • Adjunct Associate Professor, Department of Genetics and Biochemistry, Clemson University, 2018-present

Awards and Honors

  • Recipient of William H. Keck Post-doctoral Fellowship, Washington University, 2002-2003
  • Recipient of Merlie Fund Post-doctoral Fellowship, Washington University, 2003-2004
Lucy's Story

Lucy's Story

When our daughter Lucy had a metabolic crisis at 7 days old, we were shocked and devastated to find out that she was born with a rare genetic disorder (MSUD). Her newborn screening results did not make it back in time to prevent the crisis, and no one at our local hospital was familiar with the disease. They did not know how to treat her. Calls were made to Greenwood Genetic Center to confirm her diagnosis...

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