FISH can be performed on any tissue that can be cultured for chromosome analysis, including blood, fibroblasts, amniotic fluid, and chorionic villus sampling. Follow collection and transport guidelines specific for each tissue type. Studies requested should be indicated at the time of sample submission.
Prenatal testing will be considered on a case-by-case basis as the lab would like to ensure there is an appropriate indication before accepting a prenatal specimen for testing. Appropriate indications include abnormal ultrasound findings, abnormal NIPT result, and/or family history with a known/identified genetic etiology. Contact the laboratory prior to sending a prenatal specimen to discuss your case with a lab genetic counselor.