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Non-Hodgkins Lymphoma (NHL) Panel

Test Information

Non-Hodgkins Lymphoma (NHL) is a FISH analysis that screens for t(14;18), t(8;14), del p53, trisomy 8, trisomy12 when NHL is suspected. It can also be used to look for minimal residual disease in patients undergoing treatment or in patients thought to be going into or coming out of remission.

Turnaround Time

7 days

CPT Code(s)

88275 x3, 88271 x9, 88291

Cost

$1,868

Chromosomes

3q27 [BCL-6]

t(8,14) [IgH/MYC/CEP 8]

t(14,18) [IgH/BCL2]

t(11,14) [BCL1/IGH]

{CCNDXT-1/IGH}

Disorders

Non-Hodgkins Lymphoma (NHL)

Indications

This test serves as a screen for aneuploidy and chromosomal rearrangement associated with NHL. It can also be used to look for minimal residual disease in patients undergoing treatment or in patients thought to be going into or coming out of remission..

Methodology

fluorescent in situ hybridization (FISH)

Specimen Requirements

This oncology FISH test can be performed on whole blood (sodium heparin, green top tube), bone marrow, or lymph nodes. Follow collection and transport guidelines specific for each tissue type. Studies requested should be indicated at the time of sample submission.

Transport Instructions

Specimen should be kept at room temperature; do not freeze or refrigerate. Specimen should be sent by courier or overnight mail to arrive at the laboratory the next day.

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Have Questions? Need Support?

Call our laboratory at 1-800-473-9411 or contact one of our Laboratory Genetic Counselors for assistance.
Robin Fletcher, MS, CGC
Falecia Thomas, MS, CGC