Dean, Jane

Jane is the Statewide Coordinator for South Carolina’s Birth Defects Prevention Program. She works closely with partner organizations including the SC Department of Disabilities and Special Needs, SC Department of Health and Environmental Control and Shriners Hospital for Children to promote the importance of folic acid in preventing neural tube defects. Jane coordinates the Neural Tube Defect (NTD) Prevention Program providing educational materials and presentations about folic acid to school and community groups. She is also responsible for monitoring neural tube defects in SC. She visits families affected by these birth defects providing support and information and offers to enroll them in the NTD study. The NTD Prevention Program has reduced the incidence of these severe birth defects of the brain and spine by nearly 60% since it began in 1992.

Contact Information

Office (864) 941-8138
Fax (864) 388-1707
[email protected]

Awards

• National Birth Defects Prevention Network – Birth Defects Education and Prevention Award, 2009.
• National Birth Defects Prevention Network – State Leadership Award, 2002.

Selected Publications

• Dean JH, Pauly R, Stevenson RE. Neural Tube Defects and Associated Anomalies before and after Folic Acid Fortification. J Pediatr 2020: 1-9.
• Spellicy CJ, Norris J, Bend R, Bupp C, Mester P, Reynolds T, Dean JH, Peng Y, Alexov E, Schwartz CE, Stevenson RE, Friez MJ. Key Apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects. Europ J of Hum Gen 2018, 26: 420-427.
• Bupp CP, Sarasua SM, Dean JH, Stevenson RE. When Folic Acid Fails: Insights from 20 years of Neural Tube Defect Surveillance in South Carolina. AM J Med Genet Part A 167A: 2244-2250, 2015.
• Collins JS, Atkinson KK, Dean JH, Best RG, Stevenson RE. Long-term maintenance of neural tube defects prevention in a high prevalence state. J Pediatr 2011; 159:143-149.
• Grosse SD, Ouyang L, Collins JS, Green D, Dean JH, Stevenson RE. Economic evaluation of a neural tube defect recurrence-prevention program. Am J Prev Med 2008; 35:572-577.
• Dean JH, Collins JS, Clary NJ, Stevenson RE. Preventing the recurrence of neural tube defects in South Carolina. Proc Greenwood Genet Center 2007; 26:40-44.
• Stevenson RE, Seaver LH, Collins JS, Dean JH. Neural tube defects and associated anomalies in South Carolina. Birth Defects Res A Clin Mol Teratol 2004; 70:554-558.
• Thompson SJ, Torres ME, Stevenson RE, Dean JH, Best RG. Periconceptional multivitamin folic acid use, dietary folate, total folate and risk of neural tube defects in South Carolina. Ann Epidemiol 2003; 13:412-418.
• Collins JS, Dean JH, Seaver LH, Stevenson RE. Birth Defects and folic acid prevention. Proc Greenwood Genet Center 2001; 20:44-47.
• Stevenson RE, Allen WP, Pai GS, Best R, Seaver LH, Dean J, Thompson S. Decline in prevalence of neural tube defects in a high-risk region of the United States. Pediatrics 2000;106;677-683.
• Thompson S, Torres M, Stevenson R, Dean J, Best R. Periconceptional vitamin use, dietary folate and occurrent neural tube defected pregnancies in a high risk population. Ann Epidemiol 2000; 10:476.
• Allen WP, Stevenson RE, Thompson SJ, Dean JH. The impact of prenatal diagnosis on NTD surveillance. Prenat Diagn. 1996;16:531-535.
• Cragan JD, Roberts HE, Edmonds LD, Khoury MJ, Kirby RS, Shaw GM, Velie EM, Merz RD, Forrester MB, Williamson RA, Krishnamurti DS, Stevenson RE, ,Dean JH. Surveillance for anencephaly and spina bifida and the impact of prenatal diagnosis–United States, 1985-1994. MMWR CDC Surveill Summ. 1995;44:1-13.
• Davis BA, Bailey LB, Gregory JF 3rd, Toth JP, Dean J, Stevenson RE. Folic acid absorption in women with a history of pregnancy with neural tube defect. Am J Clin Nutr 1995;62:782-784.
• Schwartz CE, Dean J, Howard-Peebles PN, Bugge M, Mikkelsen M, Tommerup N, Hull C, Hagerman R, Holden JJ, Stevenson RE. Obstetrical and gynecological complications in fragile X carriers: a multicenter study. Am J Med Genet. 1994;51:400-402.
• Prouty LA, Rogers RC, Stevenson RE, Dean JH, Palmer KK, Simensen RJ, Coston GN, Schwartz CE. Fragile X syndrome growth, development, and intellectual function. Am J Med Genet. 1988;30:123-142.