Trisomy 18 FISH, Rule Out Mosaic (Buccal)

Test Information

Trisomy 18 FISH, Rule Out Mosaic is a cytogenetic test designed to detect varying degrees of mosaicism for chromosome 18 aneuploidy.

Turnaround Time

28 days

CPT Code(s)

88275 x2, 88271 x2, 88291

Cost

$758

Disorders

Methodology

FISH: Fluorescence in situ hybridization is a molecular cytogenetic technique in which fluorescently labeled DNA probes are hybridized to metaphase spreads or interphase nuclei.

Specimen Requirements

FISH analysis on buccal samples requires a kit provided by the Greenwood Genetic Center. Buccal cells are collected by brush and smeared onto a microscope slide using included instructions. Saliva is not accepted for this test.

Transport Instructions

Return the labeled slides in the provided packaging via USPS or other transport service at room temperature.

Have Questions? Need Support?

Call our laboratory at 1-800-473-9411 or contact one of our Laboratory Genetic Counselors for assistance.
Robin Fletcher, MS, CGC
Falecia Thomas, MS, CGC

Meet Makayla Gunn

Makayla was diagnosed with Rett Syndrome in April of 2015 at the age of two. At about 18 months, we noticed she had started some repetitive hand motions, and her pediatrician was a little concerned that she did not have many words. She had learned some sign language, and was saying ‘mama’ and ‘dada’, but that was it. Then she suddenly stopped all of that. At her 2 year old check-up, the pediatrician referred us to BabyNet, SC’s early interve...

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